Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955350 | 1.00 | CYP2C19 (0.47) | CYP2C19MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7960136 | 0.99 | CYP2C19 (0.47) | CYP2C19MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7960142 | 0.99 | CYP2C19 (0.47) | CYP2C19MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7960151 | 0.98 | CYP2C19 (0.48) | CYP2C19MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7960153 | 0.98 | CYP2C19 (0.48) | CYP2C19MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7956810 | 0.95 | CYP2C19 (0.49) | CYP2C19MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7956814 | 0.95 | CYP2C19 (0.49) | CYP2C19MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7957013 | 0.91 | CYP2C19 (0.46) | CYP2C19MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7957016 | 0.91 | CYP2C19 (0.46) | CYP2C19MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7957011 | 0.91 | CYP2C19 (0.46) | CYP2C19MAPTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331548-B1 | PREVENTION OR TREATMENT OF CYTOKINE RELATED DISEASES | SUNTORY LIMITED (JP) | 2001-12-18 | — | — | US | disclosed |
| EP-0978516-A1 | 1-CYCLOALKYL-1,8-NAPHTHYRIDIN-4-ONE DERIVATIVES WITH PHOSPHODIESTERASE IV INHIBITORY ACTIVITY | SUNTORY LIMITED (JP) | 2000-02-09 | — | — | EP | disclosed |