Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840751 | 0.84 | — | — | |
| SCHEMBL7840753 | 0.84 | — | — | |
| SCHEMBL733523 | 0.79 | SMN1; SMN2 (0.41) | CA12CA14SMN1; SMN2 | |
| SCHEMBL1439238 | 0.79 | SMN1; SMN2 (0.41) | CA12CA14SMN1; SMN2 | |
| SCHEMBL30771497 | 0.79 | SMN1; SMN2 (0.41) | CA12CA14SMN1; SMN2 | |
| SCHEMBL12137170 | 0.77 | CA12 (0.31) | CA12CA14SMN1; SMN2 | |
| SCHEMBL10201896 | 0.77 | SMN1; SMN2 (0.35) | CA12CA14SMN1; SMN2 | |
| SCHEMBL2254815 | 0.75 | — | — | |
| SCHEMBL3670330 | 0.75 | — | — | |
| SCHEMBL2252751 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281363-B1 | ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS; AUTOIMMUNE DISORDERS | HOFFMANN-LA ROCHE INC. | 2001-08-28 | — | — | US | disclosed |