Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693590 | 0.90 | CA1 (0.54) | CA1CA2ALDH1A1RAB9AMAPT | |
| SCHEMBL661882 | 0.87 | MEN1 (0.62) | CA1CA2ALDH1A1MAPK1RAB9A | |
| SCHEMBL25733667 | 0.87 | MEN1 (0.54) | CA1CA2ALDH1A1MAPK1RAB9A | |
| SCHEMBL669133 | 0.87 | PTPN11 (0.49) | CA1CA2ALDH1A1RAB9AMAPT | |
| SCHEMBL16144675 | 0.86 | CA1 (0.48) | CA1CA2ALDH1A1RAB9AMAPT | |
| SCHEMBL14679376 | 0.84 | POLB (0.54) | CA1CA2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10845806 | 0.84 | POLB (0.53) | CA1CA2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10850707 | 0.84 | CA1 (0.50) | CA1CA2ALDH1A1MAPTHDAC3 | |
| SCHEMBL23099730 | 0.84 | HDAC3 (0.47) | CA1CA2ALDH1A1RAB9AMAPT | |
| SCHEMBL5394826 | 0.84 | SMN1; SMN2 (0.58) | CA1ALDH1A1SMN1; SMN2MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265588-B1 | USE AS PHARMACEUTICALS; AS AN ANTIGEN FOR PRODUCTION OF ANTIBODIES AND IN DIAGNOSIS AND PURIFICATION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| US-6121479-A | ANTIINFLAMMATORY AND ANTICARCINOGENIC AGENTS; AUTOIMMUNE DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |
| US-5977151-A | ANTITUMOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |