Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833581 | 0.93 | GNRHR (0.89) | GNRHRMEN1KMT2A | |
| SCHEMBL7006144 | 0.90 | GNRHR (1.00) | GNRHRMEN1KMT2A | |
| SCHEMBL5138669 | 0.90 | GNRHR (0.86) | GNRHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7497376 | 0.90 | GNRHR (0.99) | GNRHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7833128 | 0.89 | GNRHR (0.85) | GNRHRMEN1KMT2A | |
| SCHEMBL7005389 | 0.89 | GNRHR (1.00) | GNRHRMEN1KMT2A | |
| SCHEMBL7828327 | 0.89 | GNRHR (1.00) | GNRHRMEN1KMT2A | |
| SCHEMBL7006717 | 0.89 | GNRHR (0.89) | GNRHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7498171 | 0.89 | GNRHR (0.88) | GNRHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7826617 | 0.89 | GNRHR (0.99) | GNRHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297255-B1 | GONADOTROPIN-RELEASING HORMONE ANTAGONIZING ACTIVITY; PREVENTING OR TREATING SEX HORMONE-DEPENDENT DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-10-02 | — | — | US | claimed |
| US-6329388-B2 | GONADOTROPIN-RELEASING HORMONE ANTAGONIZING ACTIVITY; USEFUL FOR PREVENTING OR TREATING SEX HORMONE-DEPENDENT DISEASES, E.G., SEX HORMONE-DEPENDENT CANCERS (E.G., PROSTATIC CANCER, UTERINE CANCER, BREAST CANCER, PITUITARY TUMOR) | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-11 | — | — | US | disclosed |
| US-6297255-B1 | GONADOTROPIN-RELEASING HORMONE ANTAGONIZING ACTIVITY; PREVENTING OR TREATING SEX HORMONE-DEPENDENT DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-10-02 | — | — | US | disclosed |