Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.86 |
| ▸ | MEN1 | O00255 | 2/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945854 | 0.99 | KMT2A (0.83) | KMT2AMEN1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL7956522 | 0.94 | KMT2A (0.80) | KMT2AMEN1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL7945842 | 0.88 | KMT2A (0.74) | KMT2AMEN1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL20339060 | 0.87 | KMT2A (0.88) | KMT2AMEN1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL20339052 | 0.87 | KMT2A (0.88) | KMT2AMEN1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL20340722 | 0.87 | KMT2A (0.88) | KMT2AMEN1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL30063662 | 0.86 | KMT2A (0.86) | KMT2AMEN1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL27516231 | 0.85 | KMT2A (0.85) | KMT2AMEN1SMN1; SMN2POLBMAPK1 | |
| Capobenic Acid SCHEMBL309384 | 0.84 | POLB (1.00) | KMT2AMEN1SMN1; SMN2POLBMAPK1 | |
| SCHEMBL7955082 | 0.84 | POLB (0.74) | KMT2AMEN1SMN1; SMN2POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| CN-1262685-A | Naphthyridine derivatives | OTSUKA PHARMA CO LTD (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |