Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 4/20 | 0.54 |
| ▸ | ACHE | P22303 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956696 | 1.00 | RARB (0.63) | RARBABCG2TP53TSHRPLA2G4B | |
| SCHEMBL3806005 | 0.99 | RARB (0.61) | RARBABCG2TP53TSHRPLA2G4B | |
| SCHEMBL3806008 | 0.99 | RARB (0.61) | RARBABCG2TP53TSHRPLA2G4B | |
| SCHEMBL7273131 | 0.96 | TP53 (0.60) | RARBABCG2TP53TSHRPLA2G4B | |
| SCHEMBL7242747 | 0.96 | TP53 (0.60) | RARBABCG2TP53TSHRPLA2G4B | |
| SCHEMBL9650506 | 0.96 | TP53 (0.60) | RARBABCG2TP53TSHRPLA2G4B | |
| SCHEMBL7273143 | 0.96 | TP53 (0.60) | RARBABCG2TP53TSHRPLA2G4B | |
| SCHEMBL1051794 | 0.96 | TP53 (0.60) | RARBABCG2TP53TSHRPLA2G4B | |
| SCHEMBL6361553 | 0.96 | TP53 (0.60) | RARBABCG2TP53TSHRPLA2G4B | |
| SCHEMBL22438884 | 0.96 | TP53 (0.60) | RARBABCG2TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277502-B1 | ORGANOSILICON POLYMERS; LIQUID CRYSALS | ROLIC AG (CH) | 2001-08-21 | — | — | US | disclosed |