Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 4/20 | 0.55 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.41 |
| ▸ | PTGIR | P43119 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839194 | 0.88 | PSMB5 (0.49) | PSMB5PSMB8KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL7948483 | 0.87 | PSMB8 (0.56) | PSMB5PSMB8ALDH1A1HPGDMEN1 | |
| SCHEMBL4138516 | 0.87 | PSMB5 (0.53) | PSMB5PSMB8L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3142808 | 0.86 | PSMB5 (0.52) | PSMB5PSMB8KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL10671152 | 0.86 | PSMB5 (0.52) | PSMB5PSMB8L3MBTL1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL10671160 | 0.86 | PSMB8 (0.55) | PSMB5PSMB8ALDH1A1HPGDMEN1 | |
| SCHEMBL21836357 | 0.84 | PSMB5 (0.54) | PSMB5PSMB8L3MBTL1ALDH1A1HPGD | |
| SCHEMBL16026175 | 0.84 | KDM4E (0.48) | PSMB5PSMB8KDM4EALDH1A1HPGD | |
| SCHEMBL21836382 | 0.83 | PSMB5 (0.50) | PSMB5PSMB8L3MBTL1ALDH1A1HPGD | |
| SCHEMBL20589021 | 0.83 | MAPT (0.56) | PSMB5KDM4EL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |