Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPOR | P19235 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956778 | 1.00 | HTR2A (0.46) | HTR2AGRIK1GRIK2ADAM17PAM | |
| SCHEMBL3252075 | 0.81 | HTR2A (0.56) | HTR2AGRIK1GRIK2ADAM17PAM | |
| SCHEMBL3252073 | 0.81 | HTR2A (0.56) | HTR2AGRIK1GRIK2ADAM17PAM | |
| SCHEMBL6193437 | 0.79 | HTR2A (0.54) | HTR2AGRIK1GRIK2ADAM17PAM | |
| SCHEMBL4290351 | 0.79 | HTR2A (0.54) | HTR2AGRIK1GRIK2ADAM17PAM | |
| SCHEMBL6193432 | 0.79 | HTR2A (0.54) | HTR2AGRIK1GRIK2ADAM17PAM | |
| SCHEMBL4290347 | 0.79 | HTR2A (0.54) | HTR2AGRIK1GRIK2ADAM17PAM | |
| SCHEMBL8267423 | 0.76 | GRIK1 (0.59) | HTR2AGRIK1GRIK2PAM | |
| SCHEMBL7876539 | 0.74 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL1716478 | 0.74 | HTR2A (0.59) | HTR2AGRIK1GRIK2PAMGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172064-B1 | METALLOPROTEASE INHIBITOR; ANTIARTHRITIC AGENTS, ANTIDIABETIC AGENTS; ANTITUMOR AGENTS | GLAXO WELLCOME INC. | 2001-01-09 | — | — | US | disclosed |