Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943855 | 0.94 | — | — | |
| SCHEMBL7943811 | 0.90 | EDNRB (0.58) | EDNRBEDNRA | |
| SCHEMBL7950751 | 0.89 | EDNRB (0.43) | EDNRBEDNRA | |
| SCHEMBL7944035 | 0.89 | EDNRB (0.38) | EDNRBEDNRA | |
| SCHEMBL8309785 | 0.87 | — | — | |
| SCHEMBL7954478 | 0.86 | — | — | |
| SCHEMBL7943807 | 0.85 | EDNRB (0.43) | EDNRBEDNRA | |
| SCHEMBL7950873 | 0.85 | EDNRB (0.50) | EDNRBEDNRA | |
| SCHEMBL7951956 | 0.84 | EDNRB (0.43) | EDNRB | |
| SCHEMBL7943839 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218427-B1 | AS ENDOTHELIN RECEPTOR ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0924207-A1 | CHROMENE-3-CARBOXYLATE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |