Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 11/20 | 0.66 |
| ▸ | PTGER2 | P43116 | 11/20 | 0.66 |
| ▸ | PTGER3 | P43115 | 10/20 | 0.66 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.66 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957259 | 1.00 | PTGER4 (0.66) | PTGER4PTGER2PTGER3PTGER1MAP3K7 | |
| SCHEMBL7798442 | 0.91 | PTGER2 (0.79) | PTGER4PTGER2PTGER3PTGER1GLRA1 | |
| SCHEMBL7798447 | 0.91 | PTGER2 (0.79) | PTGER4PTGER2PTGER3PTGER1GLRA1 | |
| SCHEMBL7957930 | 0.88 | PTGER4 (0.66) | PTGER4PTGER2PTGER3PTGER1HDAC8 | |
| SCHEMBL7957267 | 0.84 | PTGER4 (0.61) | PTGER4PTGER2PTGER3PTGER1L3MBTL1 | |
| SCHEMBL7804184 | 0.80 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1L3MBTL1 | |
| SCHEMBL7804191 | 0.80 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1L3MBTL1 | |
| SCHEMBL7804168 | 0.77 | PTGER4 (0.60) | PTGER4PTGER2PTGER3PTGER1LMNA | |
| SCHEMBL7804165 | 0.77 | PTGER4 (0.60) | PTGER4PTGER2PTGER3PTGER1LMNA | |
| SCHEMBL16038777 | 0.74 | PTGER3 (0.80) | PTGER4PTGER2PTGER3PTGER1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211197-B1 | CARBOXYLIC ACID OR TETRAZOLE DERIVATES; ANALGESICS, ANTIPYRETICS, AND ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | MERCK FROSST CANADA & CO. (CA) | 2001-04-03 | — | — | US | disclosed |