Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 6/20 | 0.64 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964792 | 0.92 | PTGIR (0.66) | PTGIRPTGER4PTGER1FABP4NR4A2 | |
| SCHEMBL7484083 | 0.85 | PTGIR (0.58) | PTGIRPTGER4PTGER1TBXA2RMAPK1 | |
| SCHEMBL8056766 | 0.85 | PTGIR (0.64) | PTGIRPTGER4PTGER1FABP4NR4A2 | |
| SCHEMBL7484312 | 0.83 | PTGIR (0.61) | PTGIRPTGER4PTGER1LMNATBXA2R | |
| SCHEMBL27574285 | 0.83 | PTGIR (0.56) | PTGIRPTGER4PTGER1FABP4NR4A2 | |
| SCHEMBL9007045 | 0.83 | PTGIR (0.66) | PTGIRPTGER4PTGER1FABP4NR4A2 | |
| SCHEMBL8065447 | 0.82 | PTGIR (0.82) | PTGIRPTGER4PTGER1FABP4PTGER3 | |
| SCHEMBL9006762 | 0.82 | PTGIR (0.71) | PTGIRPTGER4PTGER1FABP4PTGER3 | |
| SCHEMBL9006753 | 0.81 | PTGIR (0.69) | PTGIRPTGER4PTGER1FABP4NR4A2 | |
| SCHEMBL8066060 | 0.80 | PTGIR (0.68) | PTGIRPTGER4PTGER1FABP4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245790-B1 | ANTIINFLAMMATORY AGENTS; GASTROINTESTINAL DISORDERS; SKN DISORDERS; BONE DISORDERS; MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0989975-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| WO-2000016760-A2 | NEW USE OF PROSTAGLANDIN E2 ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-30 | — | — | WO | disclosed |
| WO-1998055468-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |