Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | AMY2A | P04746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948304 | 0.95 | CYP1A2 (0.44) | TYRCYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL7958044 | 0.93 | CYP1A2 (0.49) | TYRCYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL7958039 | 0.93 | CYP1A2 (0.49) | TYRCYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL15763100 | 0.91 | TYR (0.57) | TYRCYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL7948024 | 0.91 | TYR (0.57) | TYRCYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL10653843 | 0.91 | TYR (0.57) | TYRCYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL15781207 | 0.91 | TYR (0.57) | TYRCYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL5831830 | 0.91 | TYR (0.57) | TYRCYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL7958087 | 0.91 | TYR (0.57) | TYRCYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL9563946 | 0.91 | TYR (0.57) | TYRCYP1A2NFKB1THPOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| EP-0819135-B1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |