Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | GJB2 | P29033 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957672 | 1.00 | NT5E (0.50) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7957980 | 0.98 | NT5E (0.52) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7957983 | 0.98 | NT5E (0.52) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7957682 | 0.93 | NT5E (0.54) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7955497 | 0.93 | NT5E (0.41) | NT5EHTTMAPT | |
| SCHEMBL7955494 | 0.93 | NT5E (0.41) | NT5EHTTMAPT | |
| SCHEMBL7962386 | 0.89 | NT5E (0.52) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7962382 | 0.89 | NT5E (0.52) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL8317663 | 0.87 | NT5E (0.52) | NT5ESSTR5HTTNPC1RAB9A | |
| SCHEMBL7957678 | 0.87 | NT5E (0.52) | NT5ESSTR5HTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| EP-0819135-B1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |