Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.96 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.96 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.67 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352118 | 0.98 | ITGB1 (1.00) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL7971208 | 0.98 | ITGB1 (1.00) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL7967453 | 0.84 | ITGB1 (0.74) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL7357321 | 0.83 | ITGB1 (1.00) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL3904078 | 0.81 | ITGB1 (0.67) | ITGB1ITGA4ITGB7 | |
| SCHEMBL3904073 | 0.81 | ITGB1 (0.67) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7957800 | 0.81 | ITGB1 (1.00) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL7355597 | 0.80 | ITGB1 (0.74) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL7970886 | 0.80 | ITGB1 (1.00) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 | |
| SCHEMBL29575786 | 0.79 | ITGB1 (0.65) | ITGB1ITGA4ITGB7HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271252-B1 | ASTHMA THERAPY, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS,MULTIPLE SCLEROSIS, AUTOIMMUNE DISEASES | MERCK & CO., INC. | 2001-08-07 | — | — | US | claimed |
| US-6271252-B1 | ASTHMA THERAPY, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS,MULTIPLE SCLEROSIS, AUTOIMMUNE DISEASES | MERCK & CO., INC. | 2001-08-07 | — | — | US | disclosed |