SCHEMBL7958229

SCHEMBL7958229

CCC/C=C\C=C\c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.58
LMNA P02545 2/20 0.45
TRPA1 O75762 1/20 0.45
ALDH1A1 P00352 1/20 0.45
ALOX5 P09917 1/20 0.45
MAPK1 P28482 1/20 0.45
HTR2A P28223 3/20 0.41
RELA Q04206 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
GLA P06280 1/20 0.41
SIGMAR1 Q99720 2/20 0.41
CYP3A4 P08684 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10950999 1.00 MAOB (0.58) MAOBLMNATRPA1ALDH1A1ALOX5
SCHEMBL7550554 1.00 MAOB (0.58) MAOBLMNATRPA1ALDH1A1ALOX5
SCHEMBL10952208 0.88 MAOB (0.54) MAOBLMNATRPA1ALDH1A1ALOX5
SCHEMBL10952213 0.88 MAOB (0.54) MAOBLMNATRPA1ALDH1A1ALOX5
SCHEMBL6434563 0.86 MAOB (0.52) MAOBLMNATRPA1ALDH1A1ALOX5
SCHEMBL6434566 0.86 MAOB (0.52) MAOBLMNATRPA1ALDH1A1ALOX5
SCHEMBL3249161 0.85 MAOB (0.50) MAOBALDH1A1TDP1SMN1; SMN2
SCHEMBL489153 0.85 MAOB (0.50) MAOBALDH1A1TDP1SMN1; SMN2
SCHEMBL10696593 0.85 MAOB (0.50) MAOBALDH1A1TDP1SMN1; SMN2
SCHEMBL10696596 0.85 MAOB (0.50) MAOBALDH1A1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009146347-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2009-12-03 WO disclosed