Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971101 | 0.79 | FNTA (0.48) | TSHRPTGIRFNTAFNTB | |
| SCHEMBL14785259 | 0.72 | GPBAR1 (0.41) | PTGIRDRD2DRD4BRD4GPBAR1 | |
| SCHEMBL7968423 | 0.71 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL7971638 | 0.71 | FNTA (0.47) | MAPTFNTAFNTB | |
| SCHEMBL7268995 | 0.71 | SLC5A2 (0.44) | TSHRDRD2DRD4MAPTF10 | |
| SCHEMBL14785193 | 0.70 | PTGER1 (0.45) | PTGIRKDM4CKDM5AKDM5BDRD2 | |
| SCHEMBL14785447 | 0.70 | PTGIR (0.39) | PTGIRDRD2DRD4BRD4 | |
| SCHEMBL14785278 | 0.70 | PTGER1 (0.48) | — | |
| SCHEMBL14785265 | 0.69 | PTGER1 (0.42) | TSHRPTGIRBRD4MEN1KMT2A | |
| SCHEMBL14785069 | 0.69 | MRGPRX4 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |