SCHEMBL7958642

SCHEMBL7958642

Cc1noc(C)c1-c1[c]cc(Cl)cn1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 10/20 0.39
BRD2 P25440 1/20 0.39
CYP1A2 P05177 5/20 0.37
CYP3A4 P08684 4/20 0.37
HSD17B10 Q99714 3/20 0.37
ALOX15 P16050 2/20 0.37
ERN1 O75460 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.35
HIF1A Q16665 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
USP2 O75604 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
EP300 Q09472 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9932071 0.66 BRD4 (0.57) BRD4BRD2ERN1CREBBP
SCHEMBL16665665 0.66 BRD4 (0.40) BRD4BRD2CYP1A2CYP3A4HSD17B10
SCHEMBL14678367 0.65 BRD4 (0.66) BRD4BRD2CYP3A4LMNAL3MBTL1
SCHEMBL30522515 0.65 CYP1A2 (0.44) BRD4BRD2CYP1A2CYP3A4HSD17B10
SCHEMBL792214 0.64
SCHEMBL3656854 0.64 BRD4 (0.41) BRD4BRD2CYP1A2CYP3A4HSD17B10
SCHEMBL24054077 0.64 BRD4 (0.38) BRD4BRD2CYP1A2CYP3A4HSD17B10
SCHEMBL30166385 0.64 BRD4 (0.38) BRD4BRD2CYP1A2CYP3A4HSD17B10
SCHEMBL1030031 0.64 ABL1 (0.44) BRD4BRD2CYP1A2CYP3A4HSD17B10
SCHEMBL12301442 0.63 CYP1A2 (0.51) BRD4BRD2CYP1A2CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed