Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 13/20 | 0.60 |
| ▸ | NOS3 | P29474 | 3/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959581 | 0.85 | NPY1R (0.68) | NPY1R | |
| SCHEMBL7963527 | 0.83 | NPY1R (0.57) | NPY1RHTR2CHTR2BXBP1USP2 | |
| SCHEMBL7957048 | 0.82 | NPY1R (0.76) | NPY1R | |
| SCHEMBL7956690 | 0.82 | NPY1R (0.51) | NPY1RNOS3NOS1NOS2HTR2C | |
| SCHEMBL7957231 | 0.78 | NPY1R (0.51) | NPY1RXBP1USP2HPGD | |
| SCHEMBL7963665 | 0.76 | NPY1R (0.77) | NPY1R | |
| Hydrochloric Acid SCHEMBL7959693 | 0.74 | NPY1R (0.98) | NPY1RXBP1 | |
| SCHEMBL7958905 | 0.74 | NPY1R (0.60) | NPY1RXBP1USP2HPGD | |
| Hydrochloric Acid SCHEMBL7956631 | 0.73 | NPY1R (0.63) | NPY1R | |
| SCHEMBL7958563 | 0.73 | NPY1R (0.82) | NPY1RXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| EP-0789688-A4 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0789688-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1997009308-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |