Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 15/20 | 0.86 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491539 | 1.00 | PTGIR (0.86) | PTGIRPTGDRTBXAS1PPARDFABP4 | |
| SCHEMBL7487580 | 1.00 | PTGIR (0.86) | PTGIRPTGDRTBXAS1PPARDFABP4 | |
| SCHEMBL6612770 | 1.00 | PTGIR (0.86) | PTGIRPTGDRTBXAS1PPARDFABP4 | |
| SCHEMBL7494747 | 1.00 | PTGIR (0.86) | PTGIRPTGDRTBXAS1PPARDFABP4 | |
| SCHEMBL7491325 | 0.97 | PTGIR (0.82) | PTGIRPTGDRTBXAS1PPARDFABP4 | |
| SCHEMBL7500155 | 0.97 | PTGIR (0.81) | PTGIRPTGDRTBXAS1PPARDFABP4 | |
| SCHEMBL7496484 | 0.97 | PTGIR (0.81) | PTGIRPTGDRFABP4NR4A2RXRA | |
| SCHEMBL7491137 | 0.94 | PTGIR (0.77) | PTGIRPTGDRFABP4 | |
| SCHEMBL7489789 | 0.94 | PTGIR (0.76) | PTGIRPTGDRPPARDRXRARXRB | |
| SCHEMBL7490049 | 0.90 | PTGIR (0.79) | PTGIRPPARDNR4A2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300344-B1 | FOR THERAPEUTIC AND/OR PROPHYLACTIC TREATMENT OF ARTERIAL OBSTRUCTION, CEREBROVASCULAR DISEASE, HEPATIC CIRRHOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASE, RESTENOSIS AFTER PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY, HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| US-5972965-A | USEFUL FOR INHIBITION OF PLATELET AGGREGATION, VASODILATION, ANTIHYPERTENSIVE ACTIVITY AND PROSTAGLANDIN AGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0842161-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997003973-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |