Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950687 | 0.82 | GAA (0.40) | GAAEPHX2PIM1PIM3PIM2 | |
| SCHEMBL7950813 | 0.82 | GAA (0.37) | GAAEPHX2PIM1PIM3PIM2 | |
| SCHEMBL6176303 | 0.80 | GAA (0.40) | GAAEPHX2PIM1PIM3PIM2 | |
| SCHEMBL6179125 | 0.79 | EPHX2 (0.39) | GAAEPHX2PIM1PIM3PIM2 | |
| SCHEMBL7950643 | 0.79 | GAA (0.38) | GAAEPHX2PIM1PIM3PIM2 | |
| SCHEMBL6179174 | 0.78 | EPHX2 (0.42) | GAAEPHX2PIM1PIM3PIM2 | |
| SCHEMBL6177881 | 0.77 | GAA (0.38) | GAAEPHX2PIM1PIM3PIM2 | |
| SCHEMBL6175862 | 0.77 | HSD17B10 (0.40) | GAAEPHX2USP2HSD17B10KDM4E | |
| SCHEMBL7950958 | 0.77 | HSD17B10 (0.40) | GAAEPHX2USP2HSD17B10KDM4E | |
| SCHEMBL6176414 | 0.77 | EPHX2 (0.41) | GAAEPHX2PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |