SCHEMBL7958902

SCHEMBL7958902

OC(F)c1cccc(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.47
TSHR P16473 1/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
ADRB3 P13945 1/20 0.40
ALDH1A1 P00352 1/20 0.39
PGK1 P00558 1/20 0.39
PGK2 P07205 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC2A1 P11166 1/20 0.39
AOC3 Q16853 1/20 0.39
IDO1 P14902 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23489886 0.83 ACP3 (0.44) ACP3TSHRMEN1KMT2ALMNA
SCHEMBL23489885 0.83 ACP3 (0.44) ACP3TSHRMEN1KMT2ALMNA
SCHEMBL16961808 0.81 ACP3 (0.46) ACP3TSHRMEN1KMT2AADRB2
SCHEMBL29403128 0.81 ACP3 (0.50) ACP3TSHRMEN1KMT2ALMNA
SCHEMBL424623 0.81 ACP3 (0.50) ACP3TSHRMEN1KMT2ALMNA
SCHEMBL11606577 0.81 ACP3 (0.50) ACP3TSHRMEN1KMT2ALMNA
SCHEMBL6225449 0.81 ACP3 (0.50) ACP3TSHRMEN1KMT2ALMNA
SCHEMBL19390817 0.79 ACP3 (0.48) ACP3TSHRMEN1KMT2ALMNA
SCHEMBL27991707 0.79 ACP3 (0.44) ACP3TSHRMEN1KMT2AALDH1A1
SCHEMBL10916461 0.78 ACP3 (0.41) ACP3TSHRMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104529729-B The preparation method of the fluoro-3-chlorobenzaldehyde of a kind of 2- ZHEJIANG YONGTAI TECHNOLOGY CO., LTD. (CN) 2016-03-30 CN claimed
CN-104529729-A Preparation method for 2-fluoro-3-chlorobenzaldehyde ZHEJIANG YONGTAI TECHNOLOGY CO LTD 2015-04-22 CN claimed
CN-104529729-B The preparation method of the fluoro-3-chlorobenzaldehyde of a kind of 2- ZHEJIANG YONGTAI TECHNOLOGY CO., LTD. (CN) 2016-03-30 CN disclosed
CN-104529729-A Preparation method for 2-fluoro-3-chlorobenzaldehyde ZHEJIANG YONGTAI TECHNOLOGY CO LTD 2015-04-22 CN disclosed
US-6245761-B1 NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS ELI LILLY AND COMPANY 2001-06-12 US disclosed