Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956506 | 0.99 | HDAC6 (0.65) | HDAC6MAPTTSHRMAPK1CA12 | |
| SCHEMBL7952900 | 0.94 | HDAC6 (0.62) | HDAC6MAPTTSHRMAPK1CA12 | |
| SCHEMBL1355587 | 0.93 | HDAC6 (0.77) | HDAC6MAPTTSHRMAPK1CA12 | |
| SCHEMBL7954363 | 0.88 | MAPT (0.65) | HDAC6MAPTTSHRMAPK1CA12 | |
| SCHEMBL11245183 | 0.88 | HDAC6 (0.69) | HDAC6MAPTTSHRMAPK1CA12 | |
| Dodecyl 3,4-Dimethoxybenzoate SCHEMBL7801796 | 0.87 | HDAC6 (0.69) | HDAC6MAPTTSHRKDM4EPOLB | |
| SCHEMBL20918131 | 0.87 | HDAC6 (0.69) | HDAC6MAPTTSHRKDM4EPOLB | |
| SCHEMBL7635516 | 0.86 | HDAC6 (0.50) | HDAC6MAPTTSHRMAPK1CA12 | |
| SCHEMBL7631456 | 0.86 | HDAC6 (0.50) | HDAC6MAPTTSHRMAPK1CA12 | |
| SCHEMBL11493630 | 0.86 | HDAC6 (0.68) | HDAC6MAPTTSHRMAPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |