Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829102 | 1.00 | BACE1 (0.66) | BACE1 | |
| SCHEMBL12299209 | 0.91 | BACE1 (0.65) | BACE1 | |
| SCHEMBL12301102 | 0.87 | BACE1 (0.56) | BACE1 | |
| SCHEMBL12301104 | 0.87 | BACE1 (0.56) | BACE1 | |
| SCHEMBL12299251 | 0.86 | BACE1 (0.55) | BACE1 | |
| SCHEMBL7888986 | 0.85 | BACE1 (0.72) | BACE1 | |
| SCHEMBL12299526 | 0.85 | BACE1 (0.56) | BACE1 | |
| SCHEMBL12299520 | 0.84 | BACE1 (0.53) | BACE1 | |
| SCHEMBL7958581 | 0.83 | BACE1 (0.73) | BACE1 | |
| SCHEMBL7958882 | 0.82 | BACE1 (0.61) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |