Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959822 | 0.85 | PTGIR (0.54) | PTGIRPTGER4PTGER3PTGER1KDM4E | |
| SCHEMBL7961262 | 0.83 | PTGIR (0.66) | PTGIRPTGER4PTGER3PTGER1KDM4E | |
| SCHEMBL8066610 | 0.83 | PTGIR (0.72) | PTGIRPTGER4PTGER3PTGER1HTR1A | |
| SCHEMBL8056718 | 0.83 | PTGIR (0.72) | PTGIRPTGER4PTGER3PTGER1HTR1A | |
| SCHEMBL7949692 | 0.83 | PTGIR (0.72) | PTGIRPTGER4PTGER3PTGER1HTR1A | |
| SCHEMBL7960009 | 0.82 | TDP1 (0.42) | PTGIRPTGER4PTGER3PTGER1RXRA | |
| SCHEMBL7960392 | 0.79 | PTGIR (0.46) | PTGIRPTGER4PTGER3PTGER1RXRA | |
| SCHEMBL7479094 | 0.79 | PTGIR (0.73) | PTGIRPTGER4PTGER3PTGER1RXRA | |
| SCHEMBL9006885 | 0.79 | PTGIR (0.73) | PTGIRPTGER4PTGER3PTGER1RXRA | |
| SCHEMBL7949957 | 0.79 | PTGIR (0.73) | PTGIRPTGER4PTGER3PTGER1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245790-B1 | ANTIINFLAMMATORY AGENTS; GASTROINTESTINAL DISORDERS; SKN DISORDERS; BONE DISORDERS; MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |