Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871191 | 0.88 | FERMT2 (0.56) | FERMT2ALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL15585986 | 0.84 | SMN1; SMN2 (0.46) | FERMT2SMN1; SMN2PRSS1HDAC6KMT2A | |
| SCHEMBL30516524 | 0.82 | PRSS1 (0.49) | FERMT2ALDH1A1SMN1; SMN2TSHRPRSS1 | |
| SCHEMBL2794943 | 0.82 | PRSS1 (0.49) | FERMT2ALDH1A1SMN1; SMN2TSHRPRSS1 | |
| SCHEMBL7088249 | 0.81 | SMN1; SMN2 (0.44) | FERMT2SMN1; SMN2PRSS1HDAC6 | |
| SCHEMBL17678064 | 0.81 | KDM4E (0.45) | FERMT2ALDH1A1SMN1; SMN2PRSS1HDAC6 | |
| SCHEMBL23100614 | 0.81 | PRSS1 (0.51) | FERMT2ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL3868083 | 0.81 | FERMT2 (0.45) | FERMT2ALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL6815037 | 0.79 | FERMT2 (0.47) | FERMT2ALDH1A1NPSR1GAASMN1; SMN2 | |
| SCHEMBL419643 | 0.78 | PRSS1 (0.46) | ALDH1A1SMN1; SMN2TSHRPRSS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |