Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370365 | 0.91 | ELANE (0.60) | ELANECTSGMALT1NR3C1 | |
| SCHEMBL7963862 | 0.89 | ELANE (0.58) | ELANECTSGMALT1NR3C1 | |
| SCHEMBL6744559 | 0.89 | ELANE (0.58) | ELANECTSGMALT1NR3C1L3MBTL3 | |
| SCHEMBL7964090 | 0.85 | ELANE (0.51) | ELANESMN1; SMN2CTSG | |
| SCHEMBL7861404 | 0.85 | ELANE (0.59) | ELANECTSGMALT1NR3C1PGR | |
| SCHEMBL7339336 | 0.84 | ELANE (0.64) | ELANECTSGMALT1NR3C1L3MBTL3 | |
| SCHEMBL8430121 | 0.84 | ELANE (0.61) | ELANECTSGMALT1NR3C1 | |
| SCHEMBL7278895 | 0.82 | KMT2A (0.50) | ELANESMN1; SMN2CTSGL3MBTL1 | |
| SCHEMBL7952508 | 0.82 | ELANE (0.48) | ELANECTSG | |
| SCHEMBL7960491 | 0.81 | ELANE (0.75) | ELANESMN1; SMN2CTSGMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265381-B1 | MORPHOLINOUREA AND RELATED DERIVATIVES OF PENTAFLUOROETHYL PEPTIDES | MERRELL PHARMACEUTICALS, INC. | 2001-07-24 | — | — | US | disclosed |