Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2375954 | 0.86 | ATM (0.65) | ATML3MBTL1PBRM1 | |
| SCHEMBL2378170 | 0.81 | ATM (0.43) | ATML3MBTL1 | |
| SCHEMBL2378168 | 0.81 | ATM (0.43) | ATML3MBTL1 | |
| SCHEMBL2377505 | 0.78 | ATM (0.76) | ATML3MBTL1PBRM1 | |
| SCHEMBL16105688 | 0.78 | ATM (0.52) | ATMPBRM1 | |
| SCHEMBL7960125 | 0.75 | KDM4E (0.47) | ATML3MBTL1PBRM1 | |
| SCHEMBL19566973 | 0.73 | KDM4E (0.35) | ATM | |
| SCHEMBL1828698 | 0.69 | ATM (0.61) | ATML3MBTL1PBRM1 | |
| SCHEMBL20616577 | 0.69 | KMT2A (0.44) | — | |
| SCHEMBL7956857 | 0.68 | ATM (0.43) | ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |