Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.61 |
| ▸ | JAK1 | P23458 | 4/20 | 0.61 |
| ▸ | TYK2 | P29597 | 4/20 | 0.61 |
| ▸ | JAK3 | P52333 | 4/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973726 | 0.91 | HDAC1 (0.58) | JAK2JAK1TYK2JAK3HDAC1 | |
| SCHEMBL7960461 | 0.91 | HDAC1 (0.58) | JAK2JAK1TYK2JAK3HDAC1 | |
| SCHEMBL7960456 | 0.90 | HDAC1 (0.57) | JAK2JAK1TYK2JAK3HDAC1 | |
| Hydrochloric Acid SCHEMBL8213913 | 0.90 | HDAC1 (0.57) | JAK2JAK1TYK2JAK3HDAC1 | |
| SCHEMBL7970417 | 0.90 | HDAC1 (0.57) | JAK2JAK1TYK2JAK3HDAC1 | |
| Hydrochloric Acid SCHEMBL7974000 | 0.89 | HDAC1 (0.56) | JAK2JAK1TYK2JAK3HDAC1 | |
| Hydrochloric Acid SCHEMBL7960322 | 0.89 | HDAC1 (0.56) | JAK2JAK1TYK2JAK3HDAC1 | |
| SCHEMBL7960641 | 0.88 | HDAC1 (0.58) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| SCHEMBL7972141 | 0.88 | HDAC1 (0.58) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| Hydrochloric Acid SCHEMBL7976759 | 0.87 | HDAC1 (0.57) | HDAC1HDAC8HDAC3HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |