Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29713610 | 1.00 | GAA (0.48) | GAACD44CYP3A4TSHRTP53 | |
| SCHEMBL6471851 | 0.86 | PTK2 (0.41) | GAACD44CYP3A4TSHRTP53 | |
| SCHEMBL8526012 | 0.81 | GAA (0.50) | GAACD44CYP3A4TSHRTP53 | |
| SCHEMBL5704393 | 0.80 | CYP3A4 (0.47) | GAACYP3A4TSHRALDH1A1MAPK1 | |
| SCHEMBL28271960 | 0.79 | GAA (0.35) | GAACA12CA1CA2CA7 | |
| SCHEMBL10922033 | 0.79 | GAA (0.48) | GAACD44CYP3A4TSHRTP53 | |
| SCHEMBL30807892 | 0.78 | HSD17B10 (0.46) | GAACD44CYP3A4TSHRCA12 | |
| SCHEMBL9755707 | 0.78 | HSD17B10 (0.46) | GAACD44CYP3A4TSHRCA12 | |
| SCHEMBL10384706 | 0.75 | POLB (0.32) | GAA | |
| SCHEMBL4929798 | 0.74 | GAA (0.41) | GAACD44CYP3A4TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835589-B | Preparation method of 2,4-difluoro-3,5-dichloroaniline | 河南金鹏化工有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-111995538-B | Synthetic method of insecticide fluazuron and intermediate 2, 6-difluorobenzamide thereof | 浙江南郊化学有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-114835589-A | Preparation method of 2,4-difluoro-3,5-dichloroaniline | 河南金鹏化工有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-111995538-A | Synthetic method of insecticide fluazuron and intermediate 2, 6-difluorobenzamide thereof | 浙江南郊化学有限公司 | 2020-11-27 | — | — | CN | claimed |
| CN-109369414-B | Method for preparing teflubenzuron intermediate 3, 5-dichloro-2, 4-difluoroaniline | 江苏中旗科技股份有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-105801429-A | Preparation method for 3,5,-dichloro-2,4,-difluoroaniline | 上海北卡医药技术有限公司 | 2016-07-27 | — | — | CN | claimed |
| CN-103694700-B | The preparation method of the ternary composite electrode material that a kind of nanometer cable connects | BOHAI UNIVERSITY (CN) | 2016-01-13 | — | — | CN | claimed |
| CN-103694700-A | Preparation method of nano-cable-connected ternary composite electrode material | UNIV BOHAI | 2014-04-02 | — | — | CN | claimed |
| EP-0270965-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3,5-DICHLORO-2,4-DIFLUOROBENZENES | BAYER AG (DE) | 1992-09-02 | — | — | EP | claimed |
| US-5081288-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3,5-DICHLORO-2,4-DIFLUORO-BENZENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-14 | — | — | US | claimed |
| EP-0270965-A2 | Process for the preparation of substituted 3,5-dichloro-2,4-difluorobenzenes | BAYER AG (DE) | 1988-06-15 | — | — | EP | claimed |
| CN-118871430-A | DNA polymerase theta inhibitors and uses thereof | 西藏海思科制药有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-114835589-B | Preparation method of 2,4-difluoro-3,5-dichloroaniline | 河南金鹏化工有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-114835589-B | Preparation method of 2,4-difluoro-3,5-dichloroaniline | 河南金鹏化工有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-114835589-B | Preparation method of 2,4-difluoro-3,5-dichloroaniline | 河南金鹏化工有限公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-0255678-A1 | Process for production of benzoyl ureas | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-02-10 | — | — | EP | disclosed |
| US-4622340-A | HALOGENATED PHENYL HALOGENATED BENZOYL UREA, INSECTICIDES, FUNGICIDES | CELAMERCK GMBH & CO., KG (DE) | 1986-11-11 | — | — | US | disclosed |
| US-4457943-A | INSECTICIDES, MITICIDES | CELAMERCK GMBH & CO. KG (DE) | 1984-07-03 | — | — | US | disclosed |
| EP-0052833-B1 | UREA DERIVATIVES, PREPARATION AND USE | CELAMERCK GmbH & Co. KG (DE) | 1983-12-14 | — | — | EP | disclosed |
| EP-0052833-A1 | Urea derivatives, preparation and use | CELAMERCK GmbH & Co. KG (DE) | 1982-06-02 | — | — | EP | disclosed |