Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 19/20 | 0.58 |
| ▸ | FNTB | P49356 | 19/20 | 0.58 |
| ▸ | PGGT1B | P53609 | 15/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | NRAS | P01111 | 1/20 | 0.47 |
| ▸ | HRAS | P01112 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7847905 | 0.93 | FNTA (0.57) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL7842136 | 0.90 | FNTA (0.57) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7839493 | 0.88 | FNTA (0.60) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| Trifluoroacetic Acid SCHEMBL7839496 | 0.84 | FNTA (0.55) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7843356 | 0.83 | FNTA (0.64) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7970593 | 0.83 | FNTA (0.63) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7843181 | 0.82 | FNTA (0.58) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7841216 | 0.81 | FNTA (0.56) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7516320 | 0.80 | FNTA (0.61) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7830778 | 0.78 | FNTA (0.63) | FNTAFNTBPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248756-B1 | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. | 2001-06-19 | — | — | US | disclosed |