Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 5/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1954204 | 0.90 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9ANLRP3 | |
| SCHEMBL1952286 | 0.90 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9ANLRP3 | |
| SCHEMBL1951770 | 0.89 | ANO1 (0.48) | MEN1KMT2ANPC1RAB9ANLRP3 | |
| SCHEMBL1950114 | 0.89 | ANO1 (0.52) | MEN1KMT2ARAB9ANLRP3ANO1 | |
| SCHEMBL1954798 | 0.88 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9ANLRP3 | |
| SCHEMBL1950371 | 0.88 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9ANLRP3 | |
| SCHEMBL1953939 | 0.87 | ANO1 (0.49) | MEN1KMT2ANPC1RAB9ANLRP3 | |
| SCHEMBL1897405 | 0.87 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9ANLRP3 | |
| SCHEMBL1953075 | 0.87 | ANO1 (0.44) | MEN1KMT2ANPC1RAB9ANLRP3 | |
| SCHEMBL1952449 | 0.86 | ANO1 (0.44) | MEN1KMT2ANPC1RAB9ANLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |