Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957987 | 0.90 | PTGIR (0.63) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7960392 | 0.85 | PTGIR (0.46) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7960197 | 0.83 | PTGER4 (0.42) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL8127073 | 0.81 | PTGIR (0.49) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7959822 | 0.81 | PTGIR (0.54) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7964171 | 0.79 | PTGIR (0.73) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7960001 | 0.79 | PTGIR (0.78) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7964177 | 0.76 | PTGIR (0.68) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7949669 | 0.75 | PTGIR (0.49) | PTGIRPTGER4PTGER1PTGER3KDM4E | |
| SCHEMBL7957991 | 0.73 | PTGIR (0.67) | PTGIRPTGER4PTGER1PTGER3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245790-B1 | ANTIINFLAMMATORY AGENTS; GASTROINTESTINAL DISORDERS; SKN DISORDERS; BONE DISORDERS; MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0989975-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998055468-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |