Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 16/20 | 0.51 |
| ▸ | TACR1 | P25103 | 3/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.41 |
| ▸ | EED | O75530 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HLA-A | P04439 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387145 | 0.97 | HRH1 (0.53) | HRH1TACR1TACR2SSTR5 | |
| SCHEMBL1388865 | 0.96 | HRH1 (0.52) | HRH1TACR1 | |
| SCHEMBL7962558 | 0.94 | HRH1 (0.50) | HRH1TACR1SSTR5 | |
| SCHEMBL1387148 | 0.94 | HRH1 (0.51) | HRH1TACR1 | |
| SCHEMBL7954465 | 0.93 | HRH1 (0.49) | HRH1TACR1SSTR5HTTALDH1A1 | |
| SCHEMBL1387215 | 0.92 | HRH1 (0.49) | HRH1TACR1 | |
| SCHEMBL7963343 | 0.91 | HRH1 (0.49) | HRH1TACR1SSTR5LMNAHTT | |
| SCHEMBL1387197 | 0.91 | HRH1 (0.49) | HRH1TACR1SSTR5KCNH2 | |
| SCHEMBL7966896 | 0.90 | HRH1 (0.47) | HRH1TACR1SSTR5HTTALDH1A1 | |
| SCHEMBL7947313 | 0.88 | HRH1 (0.47) | HRH1TACR1SSTR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |