Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1590735 | 0.89 | GRIA2 (0.68) | GRIA2 | |
| SCHEMBL1422644 | 0.89 | GRIA2 (0.68) | GRIA2 | |
| SCHEMBL1423237 | 0.89 | GRIA2 (0.68) | GRIA2 | |
| SCHEMBL7967106 | 0.84 | GRIA2 (0.70) | GRIA2 | |
| SCHEMBL1590814 | 0.84 | GRIA2 (1.00) | GRIA2 | |
| SCHEMBL1592012 | 0.84 | GRIA2 (1.00) | GRIA2 | |
| SCHEMBL1590810 | 0.84 | GRIA2 (1.00) | GRIA2 | |
| SCHEMBL1591094 | 0.83 | GRIA2 (0.73) | GRIA2 | |
| SCHEMBL1591356 | 0.83 | GRIA2 (1.00) | GRIA2 | |
| SCHEMBL1590880 | 0.83 | GRIA2 (1.00) | GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297110-B1 | INDANE DERIVATIVES AS AMPA RECEPTOR MODULATORS | MERCK SHARP & DOHME (NL) | 2015-05-20 | — | — | EP | disclosed |
| WO-2009147167-A1 | INDANE DERIVATIVES AS AMPA RECEPTOR MODULATORS | N.V. ORGANON (NL) | 2009-12-10 | — | — | WO | disclosed |