Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 8/20 | 0.39 |
| ▸ | TLR3 | O15455 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 6/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 6/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 6/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27498777 | 1.00 | AKR1B1 (0.39) | AKR1B1CACNA1CTLR3ATMCACNA1F | |
| SCHEMBL7963402 | 0.87 | AKR1B1 (0.38) | AKR1B1CACNA1CTLR3MAPTMEN1 | |
| SCHEMBL6983916 | 0.87 | AKR1B1 (0.38) | AKR1B1CACNA1CTLR3MAPTMEN1 | |
| SCHEMBL7964272 | 0.87 | AKR1B1 (0.38) | AKR1B1CACNA1CTLR3MAPTMEN1 | |
| SCHEMBL7952174 | 0.87 | AKR1B1 (0.38) | AKR1B1CACNA1CTLR3MAPTMEN1 | |
| SCHEMBL7964237 | 0.87 | AKR1B1 (0.38) | AKR1B1CACNA1CTLR3MAPTMEN1 | |
| SCHEMBL4869775 | 0.81 | AKR1B1 (0.37) | AKR1B1CACNA1CTLR3ATMCACNA1F | |
| SCHEMBL4871424 | 0.81 | AKR1B1 (0.37) | AKR1B1CACNA1CTLR3ATMCACNA1F | |
| SCHEMBL4869785 | 0.81 | AKR1B1 (0.37) | AKR1B1CACNA1CTLR3ATMCACNA1F | |
| SCHEMBL4869825 | 0.81 | AKR1B1 (0.37) | AKR1B1CACNA1CTLR3ATMCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323238-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2001-11-27 | — | — | US | disclosed |