Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.56 |
| ▸ | PTPRC | P08575 | 4/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12271857 | 0.88 | TP53 (0.50) | PTPN1PTPRCPTPN2TP53ALDH1A1 | |
| SCHEMBL1907122 | 0.87 | ANO1 (0.60) | ANO1 | |
| SCHEMBL12272022 | 0.79 | TP53 (0.51) | PTPN1PTPRCPTPN2TP53ALDH1A1 | |
| SCHEMBL1905629 | 0.79 | ANO1 (0.60) | MAPTANO1 | |
| SCHEMBL7950646 | 0.77 | TP53 (0.51) | PTPN1PTPRCPTPN2TP53ALDH1A1 | |
| SCHEMBL7944015 | 0.77 | TP53 (0.47) | PTPN1PTPRCPTPN2TP53MAPT | |
| SCHEMBL1954748 | 0.77 | ANO1 (0.63) | ANO1 | |
| SCHEMBL1894867 | 0.77 | ANO1 (0.63) | ANO1 | |
| SCHEMBL1895978 | 0.77 | ANO1 (0.63) | ANO1 | |
| SCHEMBL1952323 | 0.76 | ANO1 (0.61) | TP53ALDH1A1ANO1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |