Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950010 | 0.89 | KDM4E (0.62) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL7960878 | 0.82 | KDM4E (0.87) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL7422885 | 0.82 | HPGD (0.64) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL7949782 | 0.82 | POLB (0.73) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL6222042 | 0.81 | HPGD (0.50) | POLBHPGDKMT2A | |
| Hydrochloric Acid SCHEMBL6221618 | 0.80 | HPGD (0.49) | POLBHPGDKMT2A | |
| SCHEMBL6221183 | 0.80 | HPGD (0.49) | POLBHPGDKMT2A | |
| SCHEMBL7958293 | 0.79 | HPGD (0.69) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL7410436 | 0.79 | POLB (0.65) | KDM4ENPC1MAPTRAB9APOLB | |
| Hydrochloric Acid SCHEMBL7671425 | 0.79 | HPGD (0.47) | POLBHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | claimed |
| US-6218384-B1 | FOR THERAPY OF ANXIETY, MUSCLE SPASMS, SLEEPLESSNESS, CONVULSIONS AND BENZODIAZEPINE OVERDOSES | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-04-17 | — | — | US | disclosed |
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | disclosed |