Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 4/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964812 | 0.94 | MAP3K7 (0.36) | MAP3K7AVPR2AVPR1AAVPR1BIRAK4 | |
| Hydrochloric Acid SCHEMBL7965778 | 0.93 | MAP3K7 (0.35) | MAP3K7AVPR2AVPR1AAVPR1BIRAK4 | |
| SCHEMBL7480304 | 0.93 | AVPR2 (0.38) | MAP3K7AVPR2AVPR1AAVPR1BIRAK4 | |
| SCHEMBL7975461 | 0.93 | MAP3K7 (0.37) | MAP3K7AVPR2AVPR1AAVPR1BIRAK4 | |
| SCHEMBL7473083 | 0.92 | MAP3K7 (0.37) | MAP3K7AVPR2AVPR1AAVPR1BIRAK4 | |
| SCHEMBL7474290 | 0.92 | MAP3K7 (0.37) | MAP3K7AVPR2AVPR1AAVPR1BIRAK4 | |
| SCHEMBL7482515 | 0.92 | MAP3K7 (0.34) | MAP3K7AVPR2AVPR1AAVPR1BIRAK4 | |
| SCHEMBL7597522 | 0.91 | MAP3K7 (0.36) | MAP3K7AVPR2AVPR1AAVPR1BIRAK4 | |
| SCHEMBL7480369 | 0.91 | MAP3K7 (0.36) | MAP3K7AVPR2AVPR1AAVPR1BIRAK4 | |
| Hydrochloric Acid SCHEMBL7965629 | 0.91 | MAP3K7 (0.36) | MAP3K7AVPR2AVPR1AAVPR1BIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |