Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966487 | 0.99 | CNR1 (0.48) | CNR1CNR2ELANEKCNH2RET | |
| SCHEMBL7961804 | 0.98 | CNR1 (0.49) | CNR1CNR2ELANEKCNH2RET | |
| SCHEMBL7960497 | 0.96 | CNR1 (0.51) | CNR1CNR2ELANEKCNH2RET | |
| SCHEMBL7962005 | 0.92 | CNR1 (0.48) | CNR1CNR2ELANEKCNH2RET | |
| SCHEMBL7966298 | 0.92 | CNR1 (0.48) | CNR1CNR2ELANEKCNH2RET | |
| SCHEMBL7960294 | 0.92 | CNR1 (0.48) | CNR1CNR2ELANEKCNH2RET | |
| SCHEMBL7966465 | 0.92 | CNR1 (0.48) | CNR1CNR2ELANEKCNH2RET | |
| SCHEMBL7951801 | 0.91 | CNR1 (0.47) | CNR1CNR2ELANEKCNH2KMT2A | |
| SCHEMBL7963686 | 0.88 | CNR2 (0.47) | CNR1CNR2ELANEKCNH2KMT2A | |
| SCHEMBL7951702 | 0.88 | CNR1 (0.49) | CNR1CNR2ELANEKCNH2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331548-B1 | PREVENTION OR TREATMENT OF CYTOKINE RELATED DISEASES | SUNTORY LIMITED (JP) | 2001-12-18 | — | — | US | disclosed |
| EP-0978516-A1 | 1-CYCLOALKYL-1,8-NAPHTHYRIDIN-4-ONE DERIVATIVES WITH PHOSPHODIESTERASE IV INHIBITORY ACTIVITY | SUNTORY LIMITED (JP) | 2000-02-09 | — | — | EP | disclosed |