Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.61 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961892 | 1.00 | PDE4B (0.61) | PDE4BPDE5AMEN1MAPTHPGD | |
| SCHEMBL7961802 | 0.91 | PDE4B (0.66) | PDE4BPDE5A | |
| SCHEMBL7961806 | 0.91 | PDE4B (0.66) | PDE4BPDE5A | |
| SCHEMBL7967215 | 0.90 | PDE4B (0.61) | PDE4BPDE5A | |
| SCHEMBL7967210 | 0.90 | PDE4B (0.61) | PDE4BPDE5A | |
| SCHEMBL7959099 | 0.89 | PDE4B (0.56) | PDE4BPDE5AMEN1KMT2A | |
| SCHEMBL7957600 | 0.89 | PDE4B (0.56) | PDE4BPDE5AMEN1KMT2A | |
| SCHEMBL7957602 | 0.89 | PDE4B (0.56) | PDE4BPDE5AMEN1KMT2A | |
| SCHEMBL7958477 | 0.89 | PDE4B (0.58) | PDE4BPDE5A | |
| SCHEMBL7955482 | 0.89 | PDE4B (0.58) | PDE4BPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326379-B1 | ERECTILE DYSFUNCTION; CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. | 2001-12-04 | — | — | US | disclosed |