Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 20/20 | 0.81 |
| ▸ | EDNRB | P24530 | 10/20 | 0.81 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | PDE4A | P27815 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631411 | 1.00 | EDNRA (0.81) | EDNRAEDNRBABCC3ABCC4ABCB11 | |
| SCHEMBL4630667 | 0.92 | EDNRA (0.74) | EDNRAEDNRBABCC3ABCC4ABCB11 | |
| SCHEMBL4661986 | 0.92 | EDNRA (0.76) | EDNRAEDNRBABCC3ABCC4ABCB11 | |
| SCHEMBL4632072 | 0.92 | EDNRA (0.76) | EDNRAEDNRBABCC3ABCC4ABCB11 | |
| SCHEMBL4632345 | 0.92 | EDNRA (0.76) | EDNRAEDNRBABCC3ABCC4ABCB11 | |
| SCHEMBL6971496 | 0.91 | EDNRA (0.75) | EDNRAEDNRBABCC3ABCC4ABCB11 | |
| SCHEMBL13324177 | 0.91 | EDNRA (0.86) | EDNRAEDNRBABCC3ABCC4ABCB11 | |
| SCHEMBL4632441 | 0.90 | EDNRA (0.74) | EDNRAEDNRBABCC3ABCC4ABCB11 | |
| SCHEMBL4631409 | 0.89 | EDNRA (1.00) | EDNRAEDNRBABCC3ABCC4ABCB11 | |
| SCHEMBL802427 | 0.89 | EDNRA (1.00) | EDNRAEDNRBABCC3ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248767-B1 | VASOCONSTRICTION | TEXAS BIOTECHNOLOGY CORP. | 2001-06-19 | — | — | US | disclosed |