Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795541 | 0.92 | MAPK1 (0.51) | MAPK1P4HTMBACE1KDM4EL3MBTL1 | |
| SCHEMBL721291 | 0.81 | MAPK1 (0.65) | MAPK1KDM4EL3MBTL1CFTRMAPT | |
| SCHEMBL31359497 | 0.81 | MAPK1 (0.65) | MAPK1KDM4EL3MBTL1CFTRMAPT | |
| Hydrochloric Acid SCHEMBL14125808 | 0.79 | MAPK1 (0.62) | MAPK1KDM4EL3MBTL1CFTRMAPT | |
| SCHEMBL797424 | 0.77 | P4HTM (0.60) | MAPK1P4HTMKDM4EL3MBTL1 | |
| SCHEMBL1584750 | 0.73 | MAPK1 (0.54) | MAPK1P4HTMKDM4EL3MBTL1MAPT | |
| SCHEMBL29260502 | 0.72 | MAPK1 (0.61) | MAPK1P4HTMKDM4EL3MBTL1JAK2 | |
| SCHEMBL6119180 | 0.72 | MAPK1 (0.53) | MAPK1P4HTMKDM4EL3MBTL1JAK2 | |
| SCHEMBL7942053 | 0.72 | MAPK1 (0.53) | MAPK1KDM4EL3MBTL1MAPT | |
| SCHEMBL11387629 | 0.71 | P4HTM (0.72) | MAPK1P4HTMKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-A1 | TRIAZINE-OXADIAZOLES | Novartis AG (CH) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |