Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 19/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689685 | 0.93 | NPY1R (0.85) | NPY1R | |
| SCHEMBL7692037 | 0.90 | NPY1R (0.86) | NPY1R | |
| SCHEMBL7691575 | 0.87 | NPY1R (0.70) | NPY1R | |
| SCHEMBL7692530 | 0.87 | NPY1R (0.78) | NPY1R | |
| SCHEMBL7687339 | 0.86 | NPY1R (0.77) | NPY1R | |
| SCHEMBL7689659 | 0.85 | NPY1R (0.83) | NPY1R | |
| SCHEMBL7689841 | 0.85 | NPY1R (0.77) | NPY1R | |
| Trifluoroacetic Acid SCHEMBL7686168 | 0.83 | NPY1R (0.84) | NPY1R | |
| SCHEMBL7691192 | 0.80 | NPY1R (0.79) | NPY1R | |
| SCHEMBL7689678 | 0.80 | NPY1R (0.78) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255494-B1 | SUBSTITUTED BENZIMIDAZOLES USEFUL IN TREATING OR PREVENTING CONDITIONS ASSOCIATED WITH EXCESS OF NEUROPEPTIDE Y (AROUND ARTERIES IN HEART, RESPIRATORY TRACT, GASTROINTESTINAL TRACT AND GENITOURINARY TRACT); ETIOLOGY OF PSYCHIATRIC DISORDERS | ELI LILLY AND COMPANY | 2001-07-03 | — | — | US | disclosed |