Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.45 |
| ▸ | CMA1 | P23946 | 9/20 | 0.39 |
| ▸ | CTRC | Q99895 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951070 | 0.91 | ELANE (0.43) | ELANECMA1CTRC | |
| SCHEMBL7961920 | 0.90 | ELANE (0.44) | ELANECMA1CTRC | |
| SCHEMBL4463669 | 0.88 | ELANE (0.44) | ELANECMA1CTRC | |
| SCHEMBL7960906 | 0.87 | ELANE (0.44) | ELANECMA1CTRC | |
| SCHEMBL7961580 | 0.87 | ELANE (0.47) | ELANECMA1CTRC | |
| SCHEMBL7961591 | 0.84 | ELANE (0.49) | ELANECMA1CTRC | |
| SCHEMBL7951058 | 0.84 | ELANE (0.49) | ELANECMA1CTRC | |
| SCHEMBL7950527 | 0.83 | CMA1 (0.42) | ELANECMA1CTRC | |
| SCHEMBL7962497 | 0.82 | ELANE (0.55) | ELANECTRC | |
| SCHEMBL8323709 | 0.82 | ELANE (0.55) | ELANECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271238-B1 | USEFUL IN TREATING AND PREVENTING DISEASES INVOLVING CHYMOTRYPSIN TYPE PROTEASES WHICH ARE RELATED TO ASTHMA, ALLERGY, INFLAMMATIONS, RHEUMATISM, HYPERTENSION, HEART FAILURE, MYOCARDIAL INFARCTION, AND CARDIAC HYPERTROPHY | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-0936216-A1 | NOVEL ACETAMIDE DERIVATIVES AND PROTEASE INHIBITORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-08-18 | — | — | EP | disclosed |