Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958687 | 0.86 | TBXA2R (0.50) | CA2MCL1HPGDKDM4EALDH1A1 | |
| SCHEMBL7956254 | 0.79 | MAPT (0.44) | MAPTPKMHTTNPSR1GAA | |
| SCHEMBL7958928 | 0.78 | TBXA2R (0.52) | CA2HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7958863 | 0.76 | TBXA2R (0.51) | MCL1HPGDKDM4EALDH1A1TBXA2R | |
| SCHEMBL7956738 | 0.76 | TBXA2R (0.51) | CA2HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7956160 | 0.74 | ADORA2A (0.42) | MAPTPKMHTTGAAADORA3 | |
| SCHEMBL7963013 | 0.69 | TBXA2R (0.52) | HPGDKDM4EALDH1A1TBXA2RPTGIR | |
| SCHEMBL7948850 | 0.68 | TBXA2R (0.46) | HPGDKDM4EALDH1A1SMN1; SMN2TBXA2R | |
| SCHEMBL7958749 | 0.67 | PTGIR (0.55) | HPGDKDM4EALDH1A1SMN1; SMN2TBXA2R | |
| SCHEMBL7948722 | 0.66 | TBXA2R (0.56) | HPGDKDM4EALDH1A1SMN1; SMN2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |