Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 8/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975670 | 0.91 | ECE1 (0.55) | ECE1MMEMEN1KMT2ATACR1 | |
| SCHEMBL7972405 | 0.91 | ECE1 (0.55) | ECE1MMEMEN1KMT2ATACR1 | |
| SCHEMBL7973922 | 0.86 | ECE1 (0.67) | ECE1MMEMEN1KMT2ALMNA | |
| SCHEMBL7976252 | 0.81 | TACR1 (0.52) | MEN1KMT2ATACR1KDM4ELMNA | |
| SCHEMBL25742675 | 0.78 | TACR1 (0.53) | TACR1 | |
| SCHEMBL242242 | 0.77 | TACR1 (0.71) | TACR1HSD17B10 | |
| SCHEMBL242241 | 0.77 | TACR1 (0.71) | TACR1HSD17B10 | |
| SCHEMBL7962286 | 0.77 | ECE1 (0.53) | ECE1MMEMEN1KMT2AKDM4E | |
| SCHEMBL7962288 | 0.77 | ECE1 (0.53) | ECE1MMEMEN1KMT2AKDM4E | |
| SCHEMBL7962462 | 0.77 | KLK5 (0.53) | ECE1MMEMEN1KMT2ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001077095-A2 | DERIVATIVES OF ALPHA-MERCAPTOACETAMIDE | NOVARTIS AG (CH) | 2001-10-18 | — | — | WO | disclosed |