Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691179 | 0.90 | NPY1R (0.59) | NPY1R | |
| SCHEMBL7683143 | 0.89 | NPY1R (0.64) | NPY1R | |
| SCHEMBL7684378 | 0.89 | NPY1R (0.77) | NPY1R | |
| SCHEMBL7685624 | 0.88 | NPY1R (0.63) | NPY1R | |
| SCHEMBL7688422 | 0.88 | NPY1R (0.64) | NPY1R | |
| SCHEMBL7688450 | 0.88 | NPY1R (0.75) | NPY1R | |
| SCHEMBL7687458 | 0.88 | NPY1R (0.62) | NPY1R | |
| SCHEMBL7693331 | 0.87 | NPY1R (0.73) | NPY1R | |
| SCHEMBL7690254 | 0.86 | NPY1R (0.61) | NPY1R | |
| SCHEMBL7690867 | 0.86 | NPY1R (0.63) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255494-B1 | SUBSTITUTED BENZIMIDAZOLES USEFUL IN TREATING OR PREVENTING CONDITIONS ASSOCIATED WITH EXCESS OF NEUROPEPTIDE Y (AROUND ARTERIES IN HEART, RESPIRATORY TRACT, GASTROINTESTINAL TRACT AND GENITOURINARY TRACT); ETIOLOGY OF PSYCHIATRIC DISORDERS | ELI LILLY AND COMPANY | 2001-07-03 | — | — | US | disclosed |