Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 18/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691391 | 0.94 | NPY1R (0.51) | NPY1RGPR119 | |
| SCHEMBL7692619 | 0.87 | NPY1R (0.68) | NPY1R | |
| SCHEMBL7682969 | 0.86 | NPY1R (0.68) | NPY1R | |
| SCHEMBL7691200 | 0.85 | NPY1R (0.55) | NPY1R | |
| SCHEMBL7682793 | 0.84 | NPY1R (0.49) | NPY1RCHEK2 | |
| SCHEMBL7690254 | 0.83 | NPY1R (0.61) | NPY1R | |
| SCHEMBL7692013 | 0.82 | NPY1R (0.51) | NPY1R | |
| SCHEMBL7685618 | 0.80 | NPY1R (0.68) | NPY1R | |
| SCHEMBL7686375 | 0.80 | NPY1R (0.50) | NPY1R | |
| SCHEMBL7959380 | 0.80 | NPY1R (0.51) | NPY1RGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255494-B1 | SUBSTITUTED BENZIMIDAZOLES USEFUL IN TREATING OR PREVENTING CONDITIONS ASSOCIATED WITH EXCESS OF NEUROPEPTIDE Y (AROUND ARTERIES IN HEART, RESPIRATORY TRACT, GASTROINTESTINAL TRACT AND GENITOURINARY TRACT); ETIOLOGY OF PSYCHIATRIC DISORDERS | ELI LILLY AND COMPANY | 2001-07-03 | — | — | US | disclosed |