Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 15/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 14/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958785 | 0.82 | TBXA2R (0.41) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7959241 | 0.80 | TBXA2R (0.62) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7956157 | 0.80 | TBXA2R (0.58) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7958632 | 0.79 | TBXA2R (0.44) | PTGIRTBXA2RPTGDRPTGDR2 | |
| SCHEMBL7959334 | 0.78 | PTGIR (0.60) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7958915 | 0.77 | TBXA2R (0.53) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7958913 | 0.77 | TBXA2R (0.53) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7948739 | 0.75 | KDM4E (0.41) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7948713 | 0.75 | PTGIR (0.87) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7963138 | 0.71 | TBXA2R (0.56) | PTGIRTBXA2RKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |