Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 17/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 14/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958505 | 0.94 | PTGIR (1.00) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7959451 | 0.87 | PTGIR (1.00) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7948985 | 0.87 | PTGIR (1.00) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7948621 | 0.87 | PTGIR (0.86) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7958040 | 0.87 | PTGIR (0.86) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7948480 | 0.86 | PTGIR (1.00) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7956621 | 0.86 | PTGIR (0.85) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7958576 | 0.84 | PTGIR (0.81) | PTGIRTBXA2RKDM4EPSMB8PSMB5 | |
| SCHEMBL7962535 | 0.84 | PTGIR (0.80) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7958337 | 0.82 | PTGIR (1.00) | PTGIRTBXA2RKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |